Fig. 6: Mutated ctDNA in the blood of patients and controls.
From: Accurate detection of circulating tumor DNA using nanopore consensus sequencing
a 17:7577121 G > A in Patient A (right panel of figure a) and three controls (left panel of figure a). b 17:7577095–7577123 deletion in Patient B (right panel of figure b) and two controls (left panel of figure b). c 17:7578403 C > T in Patient C (right panel of figure c) and five controls (left panel of figure c). d 17:7577121 G > A in Patient A in ddPCR. e 17:7576870 C > A in Patient B in ddPCR f 17:7578403 C > T in Patient C in ddPCR. g MRIs of patient A. White arrow indicates the primary tumor. h MRIs of patient B. Each data point is a single measurement and lines show the mean measurement per time in weeks. C indicates ‘controls’. Time indicates the time in weeks after treatment initiation. Median and 0-Maximum values in controls are depicted in yellow in the patient panels of CyclomicsSeq, to support a clear comparison between patients and controls.
