Table 1 Top 35 convergent DEGs across all conditions.

From: Transcriptomic effects of propranolol and primidone converge on molecular pathways relevant to essential tremor

Gene

Daoy PRIM Log2FC

Daoy Prim q val

Daoy Prop Log2FC

DAOY PROP q val

NPC PRIM Log2FC

NPC PRIM q val

NPC PROP Log2FC

NPC PROP q val

Stouffer’s Z (convergence)

Stouffer q val

BRD2

−1.533

9.998E−01

2.567

1.174E−230

−0.043

9.947E−01

−1.238

4.090E−02

14.178

1.430E−41

CHST12

−1.536

9.998E−01

2.076

2.961E−131

0.157

9.769E−01

−0.153

7.611E−01

11.536

4.910E−27

NOMO1

−0.834

9.998E−01

1.302

7.364E−118

−0.036

9.916E−01

−0.921

6.305E−05

8.488

7.950E−14

NFIB

−0.689

9.998E−01

1.031

2.763E−76

0.234

8.052E−01

−0.683

2.418E−01

8.352

1.910E−13

SPARC

−0.421

9.998E−01

1.125

6.794E−97

−0.094

5.354E−01

−0.232

1.258E−01

7.826

1.150E−11

SKI

−0.870

9.998E−01

1.440

7.651E−55

−0.107

8.877E−01

0.234

2.062E−01

7.780

1.380E−11

ZMIZ1

−0.575

9.998E−01

0.939

4.747E−31

0.266

5.758E−02

0.229

6.006E−01

7.590

5.180E−11

NUDT21

−0.899

9.998E−01

1.393

7.608E−117

0.036

9.819E−01

−0.887

9.690E−13

7.364

2.530E−10

TIMM13

−0.912

9.998E−01

1.303

2.058E−56

0.000

9.992E−01

−0.055

8.565E−01

7.118

1.250E−09

MYO1E

−1.328

9.998E−01

0.625

1.515E−01

0.244

3.649E−01

−2.375

4.660E−63

−7.125

1.250E−09

NONO

−0.090

9.998E−01

1.230

3.054E−60

−0.050

9.900E−01

−0.089

6.281E−01

6.929

4.370E−09

USP6NL

0.043

9.998E−01

0.737

1.463E−26

0.036

9.769E−01

0.105

6.006E−01

6.694

2.060E−08

B2M

−3.286

9.998E−01

4.482

1.548E−49

0.509

9.947E−01

−0.298

7.047E−01

6.601

3.580E−08

ARID1B

−0.647

9.998E−01

0.813

1.325E−43

0.143

4.174E−01

−0.271

1.746E−01

6.452

8.940E−08

FAT4

−0.127

9.998E−01

0.282

6.152E−01

0.351

1.695E−05

0.612

2.871E−09

6.376

1.380E−07

ARHGAP31

−0.046

9.998E−01

0.852

3.319E−35

0.147

9.918E−01

−0.299

8.664E−01

6.347

1.560E−07

GABRG2

−0.907

2.539E−01

−0.631

2.479E−01

−0.423

9.918E−01

−2.576

2.646E−10

−6.300

1.990E−07

G3BP1

−0.782

9.998E−01

0.672

5.807E−01

0.090

6.556E−01

−1.223

3.204E−41

−6.285

2.070E−07

BRD3

0.109

9.998E−01

0.937

2.216E−24

0.128

9.739E−01

0.013

9.746E−01

6.117

5.720E−07

ATF6B

−0.962

9.998E−01

2.386

4.626E−42

0.056

9.842E−01

−0.188

2.577E−01

6.088

6.510E−07

TRIM44

−0.520

9.998E−01

0.820

1.726E−36

0.044

9.947E−01

−0.011

9.777E−01

6.064

7.180E−07

AP2M1

−0.343

9.998E−01

0.782

3.849E−44

0.091

9.939E−01

−0.212

2.840E−01

5.947

1.410E−06

UTP4

−1.240

9.983E−01

2.301

1.442E−44

−0.215

7.209E−01

0.115

7.622E−01

5.910

1.690E−06

ROBO1

−0.114

9.998E−01

0.358

3.798E−05

0.326

2.230E−04

0.253

5.121E−02

5.866

2.120E−06

TNRC6B

−0.243

5.337E−01

0.844

1.741E−26

0.164

6.018E−01

0.165

4.706E−01

5.845

2.310E−06

MAP1B

−0.043

9.998E−01

0.105

3.132E−01

0.289

5.008E−09

0.273

9.399E−03

5.787

3.140E−06

KDM2B

−0.335

9.998E−01

0.081

7.684E−01

0.137

5.815E−01

−1.401

5.299E−38

−5.757

3.600E−06

PDZD8

−0.392

9.998E−01

0.839

5.705E−27

0.081

9.564E−01

0.100

7.470E−01

5.739

3.860E−06

WTIP

−0.031

9.998E−01

2.154

4.783E−19

0.203

8.879E−01

0.653

6.115E−01

5.724

4.070E−06

ACOT13

−0.556

9.998E−01

1.288

1.402E−53

−0.089

9.784E−01

−0.913

3.681E−02

5.699

4.420E−06

FSIP2

−1.581

7.308E−01

−0.171

6.495E−01

0.463

9.936E−01

−3.129

2.668E−14

−5.704

4.420E−06

CHD7

−0.319

9.998E−01

1.263

4.737E−23

0.380

3.162E−01

−0.054

8.085E−01

5.664

5.270E−06

IRX3

−0.148

9.998E−01

1.292

7.149E−23

−0.214

9.090E−01

0.368

1.240E−01

5.612

6.880E−06

SLC45A4

−0.481

9.998E−01

1.195

9.556E−25

0.147

8.415E−01

0.028

9.455E−01

5.542

9.980E−06

PLAA

−0.198

9.998E−01

0.692

3.441E−25

0.302

9.325E−01

−0.015

9.698E−01

5.535

1.010E−05

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