Fig. 5: RT-qPCR validation of selected genes and miRNAs in newly collected blood samples and tissue samples. | npj Genomic Medicine

Fig. 5: RT-qPCR validation of selected genes and miRNAs in newly collected blood samples and tissue samples.

From: Transcriptomic analyses of patient peripheral blood with hemoglobin depletion reveal glioblastoma biomarkers

Fig. 5

a, b Mean values of multiple PCR results from blood (a) and tissue (b) samples are shown in boxplots. Data for controls are shown with dots in gray, and data for GBMs are shown with dots in salmon. Box limits indicate the range of the central 50% of the data (from 75th to 25th quantiles) with the central line marking the median value. Comparisons (one-sided t-test): GBM vs. control (a) or tumor vs. normal (b). Data for samples from the same patient are connected by gray right arrow lines. c Expression of the GBM-Dx panel in the blood and tumor tissue of three GBM patients is shown in stacked bar plots. P GBM patient, Age age at blood draw, RT radiation therapy, Chemo chemotherapy, Re-RT reirradiation, Re-Op reoperation or reresection, αVEGF anti-VEGF/anti-angiogenetic therapy.

Back to article page