Fig. 2: Nucleotide and amino acid substitution patterns. | npj Genomic Medicine

Fig. 2: Nucleotide and amino acid substitution patterns.

From: Adaptive evolution of SARS-CoV-2 during a persistent infection for 521 days in an immunocompromised patient

Fig. 2

A Nucleotide substitutions are detailed by their type, given in percent. For example, “G-to-C” means that a guanine was substituted by a cytosine. B Nucleotide substitutions over time. Shown are the periods between two sequencing events, substitution numbers are normalized to substitutions per day. Month names (Mar March, Jun June, and Oct October) are followed by the abbreviated year. C Amino acid substitutions per gene. D Amino acid substitutions per gene normalized by the gene length. S(RBD) receptor binding domain of the spike protein.

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