Fig. 4: Maximum Likelihood tree.

Phylogenetic relationships between the patient’s samples were inferred by the maximum Likelihood method and the Tamura-Nei model. The tree with the highest log likelihood (−41647.52) is shown. The tree is drawn to scale, with branch lengths indicating the number of substitutions per site (see scale at the bottom). Reference = SARS-CoV-2 reference sequence Wuhan-Hu-1. Tree generation was performed with MEGA-X.