Fig. 3: Blood cell type distribution and neutrophil marker expression in Turner Syndrome (TS).
From: Elevated levels of neutrophils with a pro-inflammatory profile in Turner syndrome across karyotypes
A Granulocyte proportions estimated using DNA methylation data show significant differences, with TS 45,X and TS other karyotypes exhibiting higher granulocyte counts compared to 46,XX controls. B Neutrophil proportion analysis indicates an increased neutrophil proportion within the granulocyte population in TS groups. C Uniform Manifold Approximation and Projection (UMAP) plot from a single cell RNA sequencing dataset highlights the various blood cell types and the expression levels of neutrophil markers. D–H Gene expression levels of specific neutrophil markers (S100A9, FCGR3B, S100A8, MNDA, and SOD2) were quantified, with TS 45,X and TS other karyotypes showing elevated expression levels compared to 46,XX controls.
