Fig. 1: Distribution of total and risk DNVs and differences in paternal age between groups.
From: Understanding rare variant contributions to autism: lessons from dystrophin-deficient model
a Bar plot showing the distribution of total and risk DNVs in DMD-ASD and DMD-Control groups. Fishers’ exact test was used to test whether there was a difference between groups regarding total and risk DNVs. b Boxplot showing the distribution of paternal age between DMD-ASD and DMD-Control groups. Welch’s t test was applied to determine whether there was a difference in the mean paternal age. c Boxplot showing the distribution of rare variants for each group. Mann–Whitney test was performed to verify whether there was a difference in the average number of RRVs and synonymous variants between cases (DMD-ASD and DMD-ID) and the DMD-Control group. The DMD-ASD group presented, on average, a higher number of RRVs than DMD-Controls, after Bonferroni correction. ns = non-significant; *p value < 0.05.
