Fig. 2: Bayes factor for each variant type’s enrichment in candidate disease genes. | npj Genomic Medicine

Fig. 2: Bayes factor for each variant type’s enrichment in candidate disease genes.

From: Meta-analysis reveals transcription factors and DNA binding domain variants associated with congenital heart defect and orofacial cleft

Fig. 2

(Top) Bayes factor contribution by MisA, MisB, and pLoF variants in TADA for A CHD and B OFC in the “de novo + case/control” setting. Only positive Bayes factor contributions in candidate genes (q value < 0.1) with LOEUF < 1 are displayed (CHD: 46 genes, OFC: 22 genes). (Bottom) Number of variants in each category. BF Bayes factor, TF transcription factor.

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