Fig. 8 | npj Microgravity

Fig. 8

From: Stability of gene expression in human T cells in different gravity environments is clustered in chromosomal region 11p15.4

Fig. 8

Venn diagram of comparisons of stable gene expression between gravity conditions for the different platforms and determination of intersections of overlapping transcripts. a Ground-based facilities (GBFs): 15,441 genes are stably expressed for the comparisons simulated µg vs. 1 g GBF and 9 g vs. 1 g GBF. b 23rd DLR parabolic flight campaign: 11,890 genes are stably expressed between the comparisons μg vs. 1 g in-flight (IF), 1.8 g vs. 1 g IF and 1 g H/W ground control (GC). c TEXUS-51 sounding rocket campaign: 6846 genes show stable gene expression for the comparisons μg vs. 1 g IF, baseline (BL) vs. 1 g IF, and 1 g H/W GC vs. 1 g IF. d Intersection of stable gene expression for all analyzed platforms. The comparison of all three platforms results in an intersection value of 2255 stable expressed genes, while when comparing only the real microgravity platforms (parabolic flight and sounding rocket) 3324 genes were stably expressed over all investigated conditions. (criteria for stable gene expression: fold change in the range of ±1.1 and p-value >0.05)

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