Table 8 Influence of different types of stress on cellular- or tissue-specific gene expression^{49,50,51,52,53,54,55,56,57,58,59,60,61}

From: Stability of gene expression in human T cells in different gravity environments is clustered in chromosomal region 11p15.4

Stressor	Condition/ dose	Exposure time	Organisms/ tissues/cells	Microarray	Number of sample sets	Fold change ±	Differentially expressed transcripts	Differentially expressed transcripts in %	Reference
Altered gravity	Microgravity	20 s	Jurkat T cells	Affymetrix	67,528	1.3	279	0.41%	This study
Altered gravity	Microgravity	5 min	Jurkat T cells	Affymetrix	67,528	1.3	1873	2.77%	This study
Dengue virus infection	NA	48 h	HUVEC	Affymetrix human genome HG-U133A	22,283	4	395	1.77%	49, 53
Deoxynivalenol	5–25 mg/kg	3–24 h	Thymuses, C57Bl6 mice	4 × 44K whole-genome mouse oligo microarrays G4122F, Agilent	39,430	1.5	0–1707	0–4.33%	50, 54
Deoxynivalenol	0.25–0.5 µM	3–24 h	Jurkat T cells	4 × 44K human whole-genome Agilent microarray	27,958	1.5	24–578	0.09–2.07%	51, 55
Deoxynivalenol	2–4 µM	6–24 h	PBMC	4 × 44K human whole-genome Agilent microarray	27,958	1.5	487–938	1.74–3.36 %	52, 56
Giardia lamblia incubation	NA	1.5–18 h	Caco-2 cells	Affymetrix GeneChips Human Genome Focus Array	8746	2	24–214	0.27–2.45 %	52, 56
Heat shock	42 °C	1 h	Human peripheral lymphocytes	NA	4224	2.5	76	1.80%	53, 57
Exercise	NA	30 min exercise	PBMC human	Affymetrix HU133A GeneChip	>47,000	No threshold	311	0.66%	54, 58
Exercise	NA	After 60 min post-exercise	PBMC human	Affymetrix HU133A GeneChip	>47,000	No threshold	552	1.17%	54, 58
Tobacco smoke	NA	5 min exposure to smoke	PBMC human	NA	30,000	No threshold	153	0.51%	55, 59
Western style diet	NA	3 months	C57Bl/6J mice	Sentrix MouseRef-8 v1 24K Expression BeadChips (Illumina)	25,600	1.2	248	0.97%	56, 60
Western style diet	NA	6 months	C57Bl/6J mice	Sentrix MouseRef-8 v1 24K Expression BeadChips (Illumina)	25,600	1.2	121	0.47%	56, 60
Glucocorticoid stimulated with dexamethasone	10⁷ M	18 h	PBMCs	GEM microarray Incyte, St. Louis, MO	9182	1.4	1970	21.46%	57, 61
Hypoxia	1% O₂	16 h	Primary human monocytes	Affymetrix Human Genome-U133A 2.0 GeneChips	22,283	1.5	1213	5.44%	58, 62
Ionizing radiation	5 Gy	4 h post irradiation	Human lymphoblastoid cell lines	Affymetrix U95A_v2 GeneChip microarray	12,625	1.3	526	4.17%	59, 63
Ultraviolet radiation	10 J/m²	24 h post UV exposure	Human lymphoblastoid cell lines	Affymetrix U95A_v2 GeneChip microarray	12,625	1.3	1113	8.82%	59, 63
Neutron radiation	0.25 Gy	Day 1–7 post-irradiation	Mouse blood	Agilent Mouse Gene Expression 4 × 44K v2 Microarray Kit (G4846A)	39,430	1.5	46–691	0.12–1.75%	60, 64
Neutron radiation	1 Gy	Day 1–7 post irradiation	Mouse blood	Agilent Mouse Gene Expression 4 × 44K v2 Microarray Kit (G4846A)	39,430	1.5	1956–6226	4.96–15.79%	60, 64
X-ray radiation	1 Gy	Day 1–7 post irradiation	Mouse blood	Agilent Mouse Gene Expression 4 × 44K v2 Microarray Kit (G4846A)	39,430	1.5	563–765	1.43–1.94%	60, 64
X-ray radiation	4 Gy	Day 1–7 post irradiation	Mouse blood	Agilent Mouse Gene Expression 4 × 44K v2 Microarray Kit (G4846A)	39,430	1.5	1585–3577	4.02–9.07%	60, 64
Radiation (60 Co)	10 Gy / 5 × 2 Gy	24 h post irradiation	MCF7 breast carcinoma	Custom made #	7680	1.5	1229/1049	16.00/13.67%	61, 65
Radiation (60 Co)	10 Gy / 5 × 2 Gy	24 h post irradiation	DU145 prostate carcinoma	Custom made #	7680	1.5	614/881	7.99/11.47%	61, 65
Radiation (60 Co)	10 Gy / 5 × 2 Gy	24 h post irradiation	SF539 gliosarcoma	Custom made #	7680	1.5	611/1162	7.96/5.13%	61, 65

NA not applicable, no threshold no threshold is stated for fold change, i.e., all significant differentially expressed genes were considered for the analysis
#Incyte UniGEM2 set (Fremont, CA) and Research Genetics Named Genes set (Huntsville, AL)

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Table 8 Influence of different types of stress on cellular- or tissue-specific gene expression^{49,50,51,52,53,54,55,56,57,58,59,60,61}

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