Table 3 Inter and Intra-observer Reproducibility of Optic Nerve Diameter, Optic Nerve Sheath Diameter and Area of the Optic Nerve Subarachnoid Space Measurements.

From: Quantitative ultrasound image assessment of the optic nerve subarachnoid space during 90-day head-down tilt bed rest

Measurements

Interobserver Difference (95%LoA),mm

ICC (95%CI)

Intra-observer Difference (95%LoA),mm

ICC (95%CI)

ONSD 3, mm

−0.02 (−0.06,-0.01)

0.87 (0.82,0.91)

0.01 (−0.02,0.04)

0.96 (0.94,0.97)

ONSD 5, mm

−0.11 (−0.05,-0.02)

0.72 (0.61,0.8)

0.01 (−0.03,0.05)

0.91 (0.87,0.94)

OND 3, mm

−0.02 (−0.07,0.05)

0.85 (0.79,0.89)

0.01 (−0.03,0.3)

0.91 (0.87,0.94)

OND 5, mm

−0.04 (−0.07,-0.01)

0.88 (0.83,0.92)

−0.02 (−0.07,0.04)

0.81 (0.73,0.87)

ONSSA 3–5, mm2

−0.07 (−0.12,-0.02)

0.86 (0.79,0.90)

0.03 (0.00,0.06)

0.95 (0.92,0.96)

  1. ONSD 3/5 = optic nerve sheath diameter at 3 mm or 5 mm behind the optic disc.
  2. OND 3/5 = optic nerve diameter at 3 mm or 5 mm behind the optic disc.
  3. ONSSA 3–5 = the area of the optic subarachnoid space from 3 mm to 5 mm behind the optic disc.
  4. LoA limits of agreement, ICC intraclass correlation coefficient.
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