Table 1 ROI based analysis

	HDT + AG		Group		HDT		Age		Sex
ROI	β	p	β	p	β	p	β	p	β	p
L Middle Temporal	−0.001	0.896	−0.053	0.680	0.003	0.143	−0.004	0.504	0.063	0.896
L Insula	0.001	0.532	−0.156	0.079	−0.001	0.632	−0.001	.930	0.046	0.524
L Post-central	−0.012	0.199	−0.232	0.543	0.001	0.935	−0.138	0.378	−0.412	0.200
L Superior Frontal	−0.001	0.842	−0.280	0.042	0.001	0.641	0.001	0.843	−0.052	0.630
L Middle Frontal	−0.005	0.143	−0.013	0.923	0.001	0.773	0.001	0.846	0.046	0.687
R Angular Gyrus	−0.001	0.670	−0.021	0.857	0.001	0.731	−0.002	0.701	−0.012	0.905
R Rolandic Operculum	0.001	0.593	−0.238	0.108	−0.003	0.427	0.005	0.504	−0.050	0.713
R Insula	0.002	0.670	−0.267	0.143	−0.002	0.300	−0.014	0.080	−0.009	0.952
R Pre-central Gyrus	0.002	0.468	−0.294	0.044	−0.001	0.691	0.005	0.468	−0.115	0.277
L OP2	0.005	0.191	−0.342	0.046	−0.002	0.408	−0.001	0.881	−0.076	0.571
R OP2	0.006	0.183	−0.109	0.650	−0.003	0.329	−0.003	0.818	−0.201	0.368
R Lobule VI	−0.005	0.037	0.067	0.518	0.001	0.647	−0.005	0.229	−0.099	0.247

Values that are significant are bolded under the effect. ROI is the region of interest that is being assessed in each respective column. HDT + AG refers to the group by time interaction of artificial gravity impacting the effects of HDT. HDT refers to the effects of time spent in the HDT environment. Beta values are listed under β to inform direction and strength of the relationship, while statistical values are listed under p. R and L are Right and Left, respectively.

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