Table 5 Summary of analysis of long-wave infrared thermography (LWIT) tissue temperature gradient data captured by LWIT and wound imaging device at different anatomic areas of interest (AOIs), based on an LWIT color thermal energy gradient scale from –7 °C to 7 °C for the AOI
Timepoint | Head/neck | Proximal leg | |||
|---|---|---|---|---|---|
Front | Left | Right | Left | Right | |
Baseline | |||||
Median Interquartile range Marginal mean (SE) | 0.75 0.02–1.15 0.65 (0.17) | 1.07 0.77–1.22 0.93 (0.12) | 1.50 1.37–1.73 1.43 (0.12) | −0.65 −0.82 to −0.37 −0.56 (0.11) | −0.88 −1.20 to −0.63 −0.82 (0.13) |
Post-30 min | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.88 0.57–0.92 0.79 (0.09) 0.14 −0.11–0.39 0.366 | 0.80 0.58–1.15 0.88 (0.12) −0.05 −0.33 to −0.01 0.791 | 1.27 1.02–1.68 1.25 (0.12) −0.18 −0.35–0.24 0.080 | −0.57 −0.90 to −0.20 −0.63 (0.16) −0.07 −0.29–0.15 0.603 | −0.82 −1.17 to −0.43 −0.81 (0.13) 0.02 −0.19–0.23 0.896 |
Post-60 min | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.70 0.43–0.93 0.65 (0.10) 0.00 −0.30–0.30 0.995 | 0.64 0.45–0.85 0.65 (0.07) −0.28 −0.46 to −0.09 0.016 | 1.23 0.87–1.50 1.14 (0.10) −0.29 −0.52 to −0.06 0.037 | −0.88 −0.93 to −0.22 −0.71 (0.12) −0.15 −0.38–0.08 0.298 | −1.13 −1.33 to −0.92 −1.09 (0.09) −0.27 −0.52 to −0.02 0.081 |
Post-90 min | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.42 0.20–0.70 0.43 (0.12) −0.23 −0.56–0.11 0.267 | 0.61 0.05–0.72 0.47 (0.14) −0.46 −0.79 to −0.13 0.023 | 1.03 0.82–1.46 0.89 (0.24) −0.54 −0.89 to −0.19 0.011 | −0.84 −0.93 to −0.72 −0.75 (0.13) −0.9 −0.52–0.15 0.364 | −1.06 −1.30 to −0.83 −0.86 (0.20) −0.04 −0.44–0.36 0.874 |
Post-120 min | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.43 0.22–0.58 0.30 (0.13) −0.35 −0.68 to −0.02 0.084 | 0.72 0.27–0.93 0.62 (0.11) −0.31 −0.57 to −0.05 0.049 | 1.09 0.68–1.47 1.11 (0.15) −0.32 −0.52 to −0.12 0.009 | −0.93 −1.20 to −0.75 0.94 (0.10) −0.38 −0.61 to −0.15 0.007 | −1.28 −1.68 to −1.03 −1.33 (0.13) −0.51 −0.79 to −0.23 0.003 |
Post-150 min | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.30 −0.02–0.57 0.09 (0.19) −0.56 −0.96 to −0.17 0.018 | 0.39 0.07–0.65 0.40 (0.11) −0.53 −0.82 to −0.25 0.002 | 1.35 1.07–1.60 1.22 (0.13) −0.21 −0.43–0.02 0.131 | −0.75 −1.18 to −0.70 −0.89 (0.10) −0.33 −0.57 to −0.08 0.027 | −1.23 −1.53 to −0.90 −1.23 (0.13) −0.41 −0.62 to −0.19 0.002 |
Post-180 min | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.36 0.00–0.68 0.28 (0.16) −0.38 −0.70 to −0.05 0.058 | 0.48 0.08–0.80 0.47 (0.12) −0.46 −0.73 to −0.20 0.004 | 1.33 0.95–1.75 1.28 (0.15) −0.15 −0.39–0.08 0.289 | −0.96 −1.23 to −0.67 −1.01 (0.13) −0.45 −0.72 to −0.18 0.006 | −1.15 −1.43 to −1.02 1.23 (0.13) −0.41 −0.74 to −0.08 0.039 |
Post-195 min (Post-MLD) | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.78 0.48–0.95 0.63 (0.16) −0.02 −0.30–0.26 0.918 | 0.58 0.45–0.95 0.68 (0.08) −0.25 −0.46 to −0.04 0.047 | 1.28 1.18–1.42 1.35 (0.08) −0.08 −0.31–0.14 0.546 | −1.32 −1.43 to −0.87 −1.14 (0.12) −0.58 −0.86 to −0.30 0.001 | −1.47 −1.60 to −0.98 −1.39 (0.17) −0.56 −0.86 to −0.27 0.002 |
Post-225 min (30-minutes Post-MLD) | |||||
Median Interquartile range Marginal mean (SE) Mean % change from baseline 90% confidence interval P value | 0.15 −0.23–0.52 0.19 (0.14) −0.46 −0.79 to −0.14 0.019 | 0.83 0.73–1.00 0.84 (0.09) −0.09 −0.34–0.15 0.525 | 1.21 0.88–1.37 1.21 (0.12) −0.22 −0.44–0.01 0.118 | −1.43 −1.69 to −1.02 −1.45 (0.15) −0.89 −1.16 to −0.62 0.000 | −1.28 −1.79 to −0.84 −1.30 (0.19) −0.48 −0.83 to −0.12 0.027 |
