Fig. 4: Effect of AR on mechanical properties of tibias in HLU mice.

a Schematic diagram of three-point bending test of bone mechanical properties. b Results of measurements of maximum load, modulus of elasticity, stiffness, and load-deflection curves of the tibias in HLU mice. Values are mean ± SD (n = 6). * indicates P < 0.05, ** indicates P < 0.01, *** indicates P < 0.001.