Fig. 1: Establishment of a mouse disuse osteoporosis model using the HLU/Tail-suspension method. | npj Microgravity

Fig. 1: Establishment of a mouse disuse osteoporosis model using the HLU/Tail-suspension method.

From: BMP9 attenuates microgravity-related disuse osteoporosis by modulating TGFβ and BMP signaling

Fig. 1

A Micro-CT reconstruction image. B Micro-CT analysis (n = 6). C Morphology of distal femoral bone tissue, H.E. staining, TRAP staining, AB-PAS staining and silver nitrate staining. GP Growth Plate. D Cortical bone and bone marrow TGFβ1 immunohistochemistry, p-Smad2/3 immunohistochemistry, and p-Smad1/5/8 immunohistochemistry. Scale bar: Black/Red 50 μm. *p < 0.05, **p < 0.01, ***p < 0.001.

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