Fig. 2: Longitudinal evolution of the mechanical performance and hemodynamic parameters throughout the study. | npj Microgravity

Fig. 2: Longitudinal evolution of the mechanical performance and hemodynamic parameters throughout the study.

From: Evidence of effective cardiovascular countermeasures during spaceflights: insights from wearable monitoring

Fig. 2

A integral of kinetic energy measured during systole; B integral of kinetic energy measured during diastole; C systolic blood pressure; D diastolic blood pressure; E stroke volume computed with Kubicek formula normalized by the baseline sitting value; F cardiac output computed with Kubicek formula normalized by the baseline sitting value. Measurements are taken at baseline (BDC), during the flight on day 6 ± 2, 37 ± 4, and 159 ± 4 (F6, F37, and F159, respectively), and during recovery at 3 and 8 days post-flight (R + 3 and R + 8, respectively). Results are presented as median [first quartile; third quartile]. Statistical analysis was performed using a mixed-effects model with Holm-Sidak correction for multiple comparisons. ‡: p < 0.05 compared to supine baseline position, *: p < 0.05 compared to sitting baseline position, †: p < 0.05 compared to standing baseline position.

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