Fig. 5: On-body evaluation of the microfluidic sweat SERS chip towards personalized medicine. | npj Flexible Electronics

Fig. 5: On-body evaluation of the microfluidic sweat SERS chip towards personalized medicine.

From: Flexible microfluidic nanoplasmonic sensors for refreshable and portable recognition of sweat biochemical fingerprint

Fig. 5

a Photograph of a volunteer wearing a microfluidic SERS patch during continuous exercise. The inset indicates the portable Raman analyzer. b The user interface and c system-level beam path diagram of the portable Raman analyzer. Discrete Raman spectra of d sweat urea, lactate, and e pH as well as f the corresponding contents calculated from the above calibration curves. The color and black data correspond to measurements done by SERS and by commercial benchmark methods (urea test kit, lactate test kit, and pH meter), respectively. g Schematic showing the metabolic behavior of urea in the human body. Evaluation of the microfluidic SERS device in dietary challenges by comparing the sweat urea and serum urea h with and i without protein intake (n = 6, the points represent raw data; the five lines from bottom to top represent minimum, lower quartile, median, upper quartile and maximum, respectively).

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