Fig. 7: MRSA‑infected diabetic chronic wound model.

a Establishment of an infected diabetic wound model and its treatment process. b Colony numbers of MRSA obtained from the wounds (n = 3). Statistical data between the corresponding groups are denoted as *p < 0.05, **p < 0.01, ***p < 0.001. Error bars: standard deviation. c H&E staining of the wound tissues. d Immunohistochemistry staining of TNF-α and IL-1β and Ki-67 staining in different groups. e Representative photographs of the infected wounds with different treatments at varied time points. A full-thickness MRSA-infected wound (8 mm in diameter) is created on the back of a diabetic mice, and a black ring as a dimensional reference substance is placed on the wounds (diameter of the black ring: 8 mm). Changes in infected wound dimensions are recorded using a camera. f Wound closure rates of five groups on different days. (n = 3). Statistical data between the corresponding groups are denoted as *p < 0.05, **p < 0.01, ***p < 0.001. Error bars: standard deviation.