Table 2 Summary of All Electrode Performance Parameters
From: Long-term stability strategies of deep brain flexible neural interface
Type | Implantation Method | Substrate | Channel counts | Dimensions | Diameter/ Impedance (1 kHz) | SNR | Duration | Ref. |
---|---|---|---|---|---|---|---|---|
Single-Shank Electrode | Tungsten wire guide | PI | 128 | Cross-sectional area: 100 μm2 | 25 μm/ 100 kΩ | — | 8 months | |
Open Sheath Flexible Electrode | PI | 64/128 | 15 μm thick 1.2 mm wide | 30 μm/ 33~200 kΩ | — | 25 days | ||
Filamentous Electrode | SU-8 | 8/4 | 50 µm/10 µm wide 1 mm thick | -/- | — | At least 4 months | ||
NeuroRoots | Parylene | 32 | Single wire 7μm wide 1.5μm thick | 15 μm/ 40kΩ | 4.1 | At least 7 weeks | ||
Planar Mesh Electrode | SU8-guided | SU | 16/32 | Interconnect 10 μm wide, 1μm thick | 15 μm/ 100 kΩ | — | Lifespan of adult mouse | |
Cylindrical Mesh Electrode | Syringe injection | Hexagonal boron nitride | 32 | 1–1.2 mm wide | <10 μm/ — | 9–11 | 1 year | |
Neuron-Inspired Mesh Electrode | SU-8 | 16 | Dendrites and soma of pyramidal neuron-like cells | — | — | 3 months | ||
Semi-flexible Utah-like Electrode | Direct implantation | PI | 16 | 8 mm × 8 mm | — | — | 6 months | |
Microfluidic Semi-flexible Utah-like Electrode | Pneumatic impact | Si | 12 | 13 mm × 8 mm | -/ 374.32 kΩ | 3.5 | ||
Fully Flexible Origami Electrode | PLGA coating | PI | 33 | <20 µm thick | 400 µm²/ - | — | At least 2 days | |
Neural Fringe Electrode | PEG coating | PI | 1024 | Single microelectrode filament diameter 3 × 1.5 mm² | 10 mm/ 50 kΩ | — | At least 6 weeks | |
Bilayer Silk-Parylene Electrode | Silk fibroin layer rigidification | Parylene | 4 | 250 μm wide | 40 µm/ 9.4 kΩ | — | — | |
3D Nanomesh Electrode | Quick freezing | SU8 | 13 | — | >7 | — | ||
Liquid metal electrode | Liquid metal injection | PDMS | 3 | 30 μm thick 40μm wide | -/ 21.4 kΩ | — | — | |
Bacterial Cellulose-Based Electrodes | Adhered to brain surface | Bacterial Cellulose | 10 | Each electrode channel 20 μm wide | -/ 55.6 kΩ | — | — | |
Hydrogel Hybrid Electrodes | Water absorption softening | Hydrogel matrix (PAAm-Alg) | 3 | Waveguide diameter 105.9 µm | — | — | 6 months | |
Microporous Drug-Releasing Electrodes | — | PI | 4 | — | — | — | 5 weeks | |
Biomolecule-Modified Electrodes | PEG coating | Si | 33 | 3 μm thick | -/ 0.7 MΩ | 16 weeks |