Fig. 3
From: Parkinson’s disease associated with pure ATXN10 repeat expansion
XL-repeat-primed PCR. Repeat-primed PCR (RP-PCR) products separated on a 50-cm capillary. PCR products begin around 160 bp and occur at 5 bp intervals except at the location of repeat interruption (y-axis: signal strength; x-axis product size in bp). a RP-PCR products from the proband (III.8) indicate a regular 5 bp ladder through the entire length of resolution (1250 bp). b RP-PCR products from his affected brother (III.7) display multiple interruptions in ATTCT peaks between ~350 and 650 bp, ~675 and 725 bp, ~~750 and 900 and smaller areas between 900 and 1050 bp. The regular ATTCT ladder continues from 1050 bp through the length of resolution (1250 bp). Insets are shown at a higher resolution between 350–1250 (a′, b′) and 700–1250 bp (a″, b″)
