Fig. 3
From: Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease
Representative images of immunofluorescence to investigate axonal populations of mitochondria. Triple immunofluorescence for dopaminergic axons (tyrosine hydroxylase), mitochondrial mass (porin) and either mitochondrial complex I or IV was performed on striatal sections from cases with PD (a), DLB (b), AD (c) and Controls (d). A nuclear counterstain was used, DAPI. The mitochondria within individual axons could then be analysed using IMARIS analysis software. Scale bar represents 10 µm
