Fig. 4
From: Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease
Mitochondrial changes within surviving dopaminergic axons. Mitochondrial density per axon, based upon porin immunoreactivity was highest in cases with PD, when measured in conjunction within both COXI (a, *p = 0.0261) and NDUFB8 (b, *p = 0.0397). However there was also significant increase in the expression of both COXI (c, *p = 0.0359) and NDUFB8 (d, *p = 0.0112) in the axons of patients affected by PD. A significant increase in NDUFB8 expression was also detected in dopaminergic axons in DLB (*p = 0.01350)
