Fig. 3 | npj Parkinson's Disease

Fig. 3

From: Loss of glutamate signaling from the thalamus to dorsal striatum impairs motor function and slows the execution of learned behaviors

Fig. 3

Motor behavioral tasks. a Spontaneous locomotion in response to a novel environment by CAV2Cre-Slc17a6+/+ controls (n = 9) and CAV2Cre-Slc17a6lox/lox (n = 8) mice. b Motor coordination on a balance beam by CAV2Cre-Slc17a6+/+ controls (n = 5) and CAV2Cre-Slc17a6lox/lox (n = 9) mice. c Motor-skill learning on the rotating rotarod by CAV2Cre-Slc17a6+/+ controls (n = 11) and CAV2Cre-Slc17a6lox/lox (n = 17 mice. Data are shown as mean ± SEM. Statistical significance of genotype effects (repeated-measures two-way ANOVA) are shown in the headings of panels a and c (not significant, n.s.). Statistical significance of pairwise comparison of means from CAV2Cre-Slc17a6+/+ controls and CAV2Cre-Slc17a6lox/lox mice are shown. *p < 0.05 and **p < 0.01

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