Fig. 3
From: Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice
Evaluation of nigrostriatal TH-positive neurons in VKI mice. Representative images of TH (green) staining in striatal (a.i.) and nigral (c.i) sections of PFA perfused brain from VKI mice. No difference was detected in total levels of TH in the striatum (a.ii, 1-way ANOVA F2,6 = 0.28, p = 0.75) across genotypes, nor in the total count of TH-positive neurons in the SNpc (c.ii, 1-way ANOVA F2,13 = 0.74, p = 0.49) of the same mice. Similarly there were no differences in total level of TH in the striatum quantified with Western blotting (b, 1-way ANOVA F2,33 = 2.86, p = 0.08) shown cropped (for full-length blot see Supp. Fig. 2)
