Table 2 Median and interquartile range (IQR) of baseline pre-operative OFF-medication and post-operative ON-stimulation/OFF-medication UPDRS part III subscores for contralateral (C/L) rigidity, bradykinesia and tremor, and their sum total (total UPDRS-III), for the three groups of active contacts located dorsal to STN, within STN and in cZI
Baseline score, median (IQR) | Post-DBS score, median (IQR) | Individual percent improvement, median (IQR) | p-value | |
|---|---|---|---|---|
C/L rigidity | ||||
Dorsal to STN | 4 (1–6) | 1 (0–3) | 40% (25–100) | 0.001 |
Within STN | 5 (3–6) | 2 (1–3) | 60% (33–83) | <0.001 |
In cZI | 5 (3–6) | 2 (0–2) | 75% (38–100) | <0.001 |
Inter-group p-value | 0.308 | 0.529 | ||
C/L bradykinesia | ||||
Dorsal to STN | 9 (4–14) | 3 (1–3) | 68% (21–79) | 0.001 |
Within STN | 11 (7–15) | 3 (2–6) | 70% (33–82) | <0.001 |
In cZI | 9 (6–15) | 3 (2–5) | 62% (34–80) | 0.001 |
Inter-group p-value | 0.450 | 0.886 | ||
C/L tremor | ||||
Dorsal to STN | 5 (1–9) | 1 (0–2) | 75% (8–93) | 0.001 |
Within STN | 3 (0–4) | 0 (0–1) | 100% (50–100) | <0.001 |
In cZI | 0 (0–7) | 0 (0–2) | 71% (50–91) | 0.031 |
Inter-group p-value | 0.066 | 0.287 | ||
C/L total UPDRS-III | ||||
Dorsal to STN (n = 18) | 17 (12–24) | 5 (3–7) | 65% (50–74) | <0.001 |
Within STN (n = 38) | 19 (13–24) | 6 (4–10) | 69% (37–78) | <0.001 |
In cZI (n = 16) | 18 (11–22) | 6 (3–9) | 72% (51–75) | <0.001 |
Inter-group p-value | 0.810 | 0.916 | ||
