Table 2 Multiple linear regression model of bradykinesia and dyskinesia non-motor predictors defined by the non-motor symptom scale domains

	BKS		DKS
	β	P	β	P
Disease duration	0.047	0.62	0.088	0.36
Age	0.072	0.45	0.036	0.71
NMSS cardiovascular	−0.080	0.44	0.065	0.54
NMSS sleep/fatigue	−0.006	0.96	0.083	0.52
NMSS mood/cognition	0.075	0.54	−0.308	0.016
NMSS perceptual/hallucinations	−0.055	0.58	0.229	0.025
NMSS attention/memory	−0.102	0.34	−0.055	0.62
NMSS gastrointestinal tract	0.303	0.006	−0.247	0.029
NMSS urinary	0.100	0.37	0.024	0.83
NMSS sexual function	0.301	0.003	0.005	0.96
NMSS miscellaneous^a	−0.182	0.09	0.322	0.003
PDSS	0.182	0.11	0.059	0.61
HADS	−0.009	0.95	0.144	0.29
MMSE	−0.029	0.76	−0.116	0.23
ESS	0.062	0.56	−0.139	0.20
LEDD	−0.327	0.001	0.258	0.009

NMSS Non Motor Symptom Scale, LEDD levodopa equivalent dose, PDSS Parkinson’s disease sleep scale, HADS hospital and anxiety depression scale, MMSE mini mental state examination, ESS Epworth’s sleepiness scale, BKS bradykinesia score, DKS dyskinesia score
^aThe miscellaneous domain contains questions about pain, hyposmia, hyperhidrosis and weight change
Significant values are highlighted in bold

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