Fig. 3: Polymorph unwinding.
From: A series of helical α-synuclein fibril polymorphs are populated in the presence of lipid vesicles

a αS polymorph ‘helices’ are observed to unwind into ‘ribbons’ and ‘waves’. b The αS macromolecular assemblies have been observed to have frayed ends, suggesting a common building block between the different polymorphs.