Table 1 Relative changes and effect sizes from baseline to 1-, 2-, and 3-year follow-up.
Baseline to 1-year follow-up | Baseline to 2-year follow-up | Baseline to 3-year follow-up | ||||
---|---|---|---|---|---|---|
RC (%) | ES | RC (%) | ES | RC (%) | ES | |
NMSS total score | −8.87 | 0.09 | −2.94 | 0.03 | 12.09 | −0.16 |
D1: Cardiovascular | −93.33 | 0.17 | −58.18 | 0.13 | −1.16 | 0.00 |
D2: Sleep/fatigue | −1.51 | 0.01 | 14.87 | −0.14 | 19.46 | −0.20 |
D3: Mood/apathy | -45.69 | 0.20 | −43.35 | 0.19 | −22.31 | 0.11 |
D4: Perceptual problems/hallucinations | 30.43 | −0.10 | 30.43 | −0.10 | 58.97 | −0.34 |
D5: Attention/memory | 8.58 | −0.07 | 2.12 | −0.02 | 21.75 | −0.20 |
D6: Gastrointestinal | 26.36 | −0.21 | 27.76 | −0.22 | 42.42 | −0.43 |
D7: Urinary | −2.13 | 0.01 | −0.60 | 0.00 | 23.69 | −0.19 |
D8: Sexual function | −34.55 | 0.15 | −87.01 | 0.27 | −37.34 | 0.15 |
D9: Miscellaneous | 2.20 | −0.02 | 22.63 | −0.24 | 21.88 | −0.23 |