Table 1 Relative changes and effect sizes from baseline to 1-, 2-, and 3-year follow-up.

From: Longitudinal evolution of non-motor symptoms in early Parkinson’s disease: a 3-year prospective cohort study

 

Baseline to 1-year follow-up

Baseline to 2-year follow-up

Baseline to 3-year follow-up

RC (%)

ES

RC (%)

ES

RC (%)

ES

NMSS total score

−8.87

0.09

−2.94

0.03

12.09

−0.16

D1: Cardiovascular

−93.33

0.17

−58.18

0.13

−1.16

0.00

D2: Sleep/fatigue

−1.51

0.01

14.87

−0.14

19.46

−0.20

D3: Mood/apathy

-45.69

0.20

−43.35

0.19

−22.31

0.11

D4: Perceptual problems/hallucinations

30.43

−0.10

30.43

−0.10

58.97

−0.34

D5: Attention/memory

8.58

−0.07

2.12

−0.02

21.75

−0.20

D6: Gastrointestinal

26.36

−0.21

27.76

−0.22

42.42

−0.43

D7: Urinary

−2.13

0.01

−0.60

0.00

23.69

−0.19

D8: Sexual function

−34.55

0.15

−87.01

0.27

−37.34

0.15

D9: Miscellaneous

2.20

−0.02

22.63

−0.24

21.88

−0.23

  1. All domains showed small effect size from baseline to 1-, 2-, and 3-year follow-up.
  2. RC relative changes, ES effect size, NMSS non-motor symptoms scale.