Table 3 Association between baseline NMS number and motor progression in PD.

From: Longitudinal evolution of non-motor symptoms in early Parkinson’s disease: a 3-year prospective cohort study

 

Number of NMS at baseline

OR (95%CI)

P-value

UPDRS-III 3-point increase from baseline to 1-year

1.074 (1.013–1.139)

0.017*

UPDRS-III 6-point increase from baseline to 2-year

1.113 (1.048–1.182)

0.001*

UPDRS-III 9-point increase from baseline to 3-year

1.117 (1.048–1.191)

<0.001*

  1. * Significant difference.
  2. In the multivariate models, sex, age at enrollment, age of onset, disease duration, and UPDRS III score at baseline were adjusted.
  3. PD parkinson’s disease, NMS non-motor symptom, UPDRS unified Parkinson’s disease rating scale.