Table 5 Nested case-control analysis: participant characteristics and associations with delirium.
From: First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors, and outcomes
Variable | Delirium N = 105 | Not delirium N = 105 | Association with delirium | |||
|---|---|---|---|---|---|---|
Univariable analyses | Multivariable analyses | |||||
OR (95% CI) | P-value | OR (95% CI) | P-value | |||
Age at baseline in years | 77.5 (6.2)a | 77.4 (6.3)a | 1.16 (0.84–1.59) | 0.36 | 0.96 (0.61–1.53) | 0.87 |
Male sex | 69 (66)b | 69 (66)b | NA | NA | ||
Diagnosis | NA | NA | ||||
PD | 72 (69)b | 72 (69)b | ||||
Atypical parkinsonism | 33 (31) | 33 (31) | ||||
Disease duration in years | 2.6 (1.0–5.8)c | 2.7 (1.0–5.9)c | 0.81 (0.31–2.10) | 0.364 | 0.52 (0.14–1.98) | 0.34 |
Dementia present before admission | 46 (44)b | 23 (22)b | 4.28 (1.88–9.76) | 0.001 | 5.99 (1.86–19.24) | 0.003 |
Most recent MMSEd | 24 (21–27)c | 27 (22–28)c | 0.92 (0.86–0.98) | 0.015 | 1.05 (0.95–1.16) | 0.36 |
Cause of admission | ||||||
Infection | 49 (47)b | 18 (17)b | 5.45 (2.00–14.89) | 0.001 | 7.88 (1.61–38.49) | 0.01 |
Other medical | 37 (35) | 50 (48) | Reference | Reference | ||
Fracture | 15 (14) | 5 (5) | 5.66 (1.47–21.77) | 0.01 | 7.36 (2.27–23.87) | 0.001 |
Other surgical | 4 (4) | 32 (30) | 0.17 (0.04–0.77) | 0.02 | 0.16 (0.03–0.93) | 0.04 |
Emergency (vs elective) admission | 100 (95)b | 82 (78)b | 7.00 (2.09–23.47) | 0.002 | 7.36 (1.98–27.35) | 0.003 |
CRP (mg/L)d | 16 (10–57)c | 17 (10–43)c | 1.00 (1.00–1.01) | 0.86 | 1.00 (0.99–1.01) | 0.79 |
Albumin (mg/L)d | 40 (37–43)c | 40 (36–43)c | 0.98 (0.92–1.05) | 0.55 | 1.03 (0.94–1.12) | 0.54 |
