Table 2 Clinical features of Parkinson’s disease subjects and healthy control subjects.

From: Deep nasal sinus cavity microbiota dysbiosis in Parkinson’s disease

 

PD

rHC

p-value

SpPD

SpHC

p-value

Total subjects

30

17

11

11

Age

60.12 (6.86)

55.18 (11.09)

0.64

58.4 (5.09)

59.4 (5.2)

0.65

Sex (% male)

83%

71%

0.46

64%

45%

0.67

Age of onset

54.69 (8.15)

53.2 (7.88)

Disease duration

5.53 (4.81)

14.1 (19.78)

Total MDS-UPDRS

30.1 (14.1)

26.67 (9.32)

MDS-UPDRS I

5.5 (3.2)

5.58 (3.26)

MDS-UPDRS II

5.4 (4.9)

5 (2.86)

MDS-UPDRS III

17.8 (8.3)

14.25 (4.47)

MDS-UPDRS IV

1.3 (2.5)

1.83 (2.79)

H&Y Stages

1.9 (0.3)

1.82 (0.40)

LEDD

400.8 (369.6)

308.18 (245.72)

UPSIT

24.7 (6.7)

26.2 (8.36)

37 (2.7)

0.02

  1. 58 participants; Mean ± (S.D.). Statistical analyses were performed using the Students t-test (age), Chi-square test (sex), and Mann–Whitney U (UPSIT). Significant P-values (P < 0.05: bold).
  2. MDS-UPDRS Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale, H&Y Hoehn and Yahr, LEDD Levodopa Equivalent Daily Dosing, UPSIT The Smell Identification Test, PD Parkinson’s disease, rHC random non-spousal healthy controls, SpPD household Parkinson’s disease, SpHC household spousal healthy controls.