Fig. 2: Evolution of NMS after 2-year follow up.
From: Predictors of clinically significant quality of life impairment in Parkinson’s disease

A Change in the NMSS total score from V0 (baseline) to V2 (2 year ± 1 month) in PD patients without vs with clinically significant HRQoL impairment. B Mean score on each domain of the ESS scale at V0 and V2 in PD patients without vs with clinically significant HRQoL impairment. Data are presented as box plots, with the box representing the median and the two middle quartiles (25–75%). p-values were computed using the Wilcoxon-signed rank test. Mild outliers (O) are data points that are more extreme than Q1 − 1.5 * IQR or Q3 + 1.5 * IQR. NMSS, Non-Motor Symptoms Scale.