Table 1 Median and range of demographic, motor and cognitive measures including sex subgroups.

From: The emerging postural instability phenotype in idiopathic Parkinson disease

Measure

Controls

Parkinson disease

Chi-square (LR) (Y5_HY0–2 vs. Y5_HY3–5)

  

Y5_HY0–2

Y5_HY3–5

Demographics

Gender (M, F, Other)

127,62,10

187,73,17

66,33,4

NS

Age

62 (55,69)

61 (53,67)

67 (59,78)

p < 0.001**

Motor examination

UPDRS I

2 (0,4)

3 (1,5)

(3,8)

p < 0.001**

UPDRS II

0 (0,0)

4 (2,6)

7 (4,11)

p < 0.001**

UPDRS III

0 (0,2)

18 (13,24)

22 (16,29)

p = 0.0029**

UPDRS IV

N/A

N/A

N/A

 

PIGD score

0 (0,0)

2 (1,3)

4 (2,7)

p < 0.001**

HY

0 (0,0)

0 (1,2)

2 (1,2)

NS

Cognition

MOCA

28 (27,29)

28 (26,29)

27 (25,29)

NS

HVLT total recall

26 (23,30)

26 (23,29)

24 (20,28)

NS

Delayed recall

10 (8,11)

9 (8,11)

8 (6,10)

NS

Letter Number Seq

11 (9,12)

11 (9,13)

10 (8,12)

NS

Judgment of line orientation

14 (12,15)

14 (12,15)

13 (11,14)

p = 0.026*

Symbol digit modality

46 (39,53)

43 (37,49)

37 (32,45)

p = 0.015*

Semantic fluency

52 (46,58)

51 (45,57)

50 (43,57)

NS

Letter fluency (F)

14 (11,17)

13 (11,16)

13 (11,16)

NS

  1. Raw scores are presented. All rank order statistical evaluations have been adjusted for age, sex, and multiple comparisons. Differences between individuals who later develop progressive gait dysfunction (HY stage 3 or higher by 5 years of follow up) and those who maintain stable gait function under management are reported on the far right. Underline italic is used to denote differences between PD subgroups and controls. Bold italic denotes differences between PD subgroups (right column). Statistical comparisons are adjusted using a Bonferroni correction.
  2. *p < 0.05 (Adjusted), **p < 0.005 (Adjusted).