Fig. 3: Correlations of pre-central cortex FC with pPDU. | npj Parkinson's Disease

Fig. 3: Correlations of pre-central cortex FC with pPDU.

From: Functional connectivity of the cortico-subcortical sensorimotor loop is modulated by the severity of nigrostriatal dopaminergic denervation in Parkinson’s Disease

Fig. 3

Scatterplots for PD (red) and ET (blue) patients of the mean FC of the clusters (highlighted in the inserts on the right, the most affected side is at reader’s left) showing a significant correlation of the pre-central cortex FC (y axis) with pPDU (x axis) in PD patients. For the purposes of the graph, for each contrast all clusters were averaged as they provided substantially overlapping patterns of correlation. The FC of the pre-central cortex on the MAS with the homolateral superior/mid temporal gyri and inferior occipital cortex shows a significant direct correlation with pPDU in PD patients, with no significant correlation in ET patients in the same regions (a). On the contrary, The FC of the pre-central cortex on the MAS with the thalami decreased with increasing pPDU in PD patients (b).

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