Table 1 Demographic characteristics.
From: Local striatal volume and motor reserve in drug-naïve Parkinson’s disease
Variables | Patients with PD (n = 333) | TD type (n = 76) | AR or mixed type (n = 257) | pa value |
---|---|---|---|---|
Age at symptom onset, years | 63.99 ± 9.69 | 62.25 ± 9.81 | 64.50 ± 9.62 | 0.075 |
Female subjects, no. (%) | 177 (53.1%) | 37 (48.7%) | 140 (54.5%) | 0.449 |
Disease duration, months | 16.87 ± 15.23 | 18.41 ± 15.81 | 16.45 ± 15.09 | 0.326 |
UPDRS-III score | 23.10 ± 10.45 | 20.29 ± 9.66 | 23.93 ± 10.55 | 0.007 |
Education, years | 9.49 ± 5.09 | 10.58 ± 4.85 | 9.17 ± 5.13 | 0.035 |
Striatal volume, ratio to ICV | ||||
Right caudate | 0.21 ± 0.03 | 0.21 ± 0.03 | 0.21 ± 0.03 | 0.383 |
Right putamen | 0.28 ± 0.04 | 0.29 ± 0.05 | 0.28 ± 0.04 | 0.260 |
Left caudate | 0.20 ± 0.03 | 0.20 ± 0.03 | 0.20 ± 0.03 | 0.366 |
Left putamen | 0.28 ± 0.04 | 0.28 ± 0.05 | 0.27 ± 0.04 | 0.119 |
DAT availability | ||||
Anterior caudate | 2.12 ± 0.69 | 2.25 ± 0.60 | 2.08 ± 0.71 | 0.067 |
Posterior caudate | 1.42 ± 0.57 | 1.52 ± 0.47 | 1.39 ± 0.59 | 0.049 |
Anterior putamen | 2.23 ± 0.64 | 2.41 ± 0.58 | 2.18 ± 0.65 | 0.006 |
Posterior putamen | 1.38 ± 0.47 | 1.49 ± 0.45 | 1.35 ± 0.47 | 0.015 |
Ventral putamen | 1.48 ± 0.43 | 1.58 ± 0.39 | 1.45 ± 0.43 | 0.014 |
Ventral striatum | 2.15 ± 0.61 | 2.30 ± 0.57 | 2.10 ± 0.61 | 0.015 |
MR estimates | 0.19 ± 0.57 | −0.07 ± 0.61 | 0.048 |