Table 2 Tokyo dataset.

From: A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson’s disease

SYMP

HE

ADR

DMV

LC

SN

NBM

AMY

TOX

CING

TEMP

# cases

# OB pos.

% OB pos.

EARLY AMYGDALA-PREDOMINANT CASES

       

x

   

11

9

82

x

      

x

   

2

2

100

x

x

     

x

   

1

1

100

       

x

x

  

2

1

50

      

x

x

   

1

1

100

    

x

  

x

   

1

1

100

      

x

x

x

  

1

1

100

       

x

x

x

 

1

1

100

     

x

 

x

x

  

1

1

100

     

x

x

x

   

2

2

100

      

x

x

 

x

 

1

1

100

    

x

 

x

x

   

1

1

100

       

x

 

x

x

1

1

100

   

x

 

x

 

x

   

1

1

100

   

TOTAL

27

24

89

EARLY BRAINSTEM/PNS-PREDOMINANT CASES

 

x

         

1

0

0

x

          

5

0

0

x

x

         

3

0

0

   

x

       

1

0

0

x

x

 

x

       

1

0

0

x

x

x

x

       

2

0

0

x

   

x

      

1

0

0

   

x

x

      

4

0

0

 

x

 

x

x

      

1

0

0

   

x

x

  

x

   

1

1

100

   

x

x

 

x

    

1

0

0

x

  

x

x

 

x

    

1

0

0

x

x

x

x

 

x

     

1

1

100

   

TOTAL

23

2

9

EARLY OTHER CASES

    

x

      

1

1

100

     

x

     

1

1

100

    

x

x

     

1

0

0

   

TOTAL

3

2

67

  1. The Tokyo dataset had 53 early-stage ILBD cases with minimal Lewy-type pathology ordered into amygdala-predominant, brainstem/PNS-predominant cases, and other cases categories. An “x” signifies the presence of Lewy-type pathology in individual anatomical structures. For further details including some abbreviations, see Table 1 legend.
  2. SYMP sympathetic trunk, HE heart, ADR adrenal gland, NBM nucleus basalis of Meynert, CING anterior cingulum, TEMP temporal cortex.