Fig. 3: Selectivity of aSyn antibodies over aSyn conformations. | npj Parkinson's Disease

Fig. 3: Selectivity of aSyn antibodies over aSyn conformations.

From: Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases

Fig. 3

a Representative EM images of aSyn human WT monomers, oligomers and fibrils. b DB and WB characterization of 18 aSyn antibodies to determine their conformational selectivity using aSyn human WT recombinant monomers, oligomers and fibrils. aSyn alpha-synuclein, DB dot/slot blot, EM electron microscopy, f fibrils, m monomers, o oligomers, WB Western blot, WT wild-type.

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