Table 1 Patient demographics and clinical characteristics.

From: Cortical thickness and white matter microstructure predict freezing of gait development in Parkinson’s disease

Characteristic

Level

PPMI

FJMUUH-PD

P-value

n = 85

n = 55

Age at baselinea

–

59.6 (10.6)

65.7 (7.1)

<0.001

Sex (%)b

Female

32.0 (37.6)

26.0 (47.3)

0.259

 

Male

53.0 (62.4)

29.0 (52.7)

–

Years of educationc

–

16.0 [14.0,18.0]

9.0 [6.0,12.0]

<0.001

H&Y (%)b

<2

45.0 (52.9)

16.0 (29.1)

0.005

 

≥2

40.0 (47.1)

39.0 (70.9)

–

MDS-UPDRS-I scoresc

–

1.0 [0.0, 2.0]

\

\

MDS-UPDRS-II scoresc

–

5.0 [2.0,7.0]

\

\

MDS-UPDRS-III scoresc

–

18.0 [13.5,24.0]

\

\

UPDRS-I scoresc

–

\

2.0 [1.0,4.0]

\

UPDRS-II scoresa

–

\

9.6 (4.9)

\

UPDRS-III scoresc

–

\

27.0 [18.0,36.0]

\

RBDSQc

–

3.0 [2.0, 5.0]

2.0 [0.0,4.0]

0.004

MoCAc

–

28.0 [26.0,29.0]

21.31 (5.4)

<0.001

MoCA (%)b

≥26

67.0 (78.8)

14.0 (25.5)

<0.001

 

<26

18.0 (21.2)

41.0 (74.6)

–

  1. Bold values represent correlations that are statistically significant.
  2. PPMI Parkinson’s Progression Marker Initiative, FJMUUH-PD Fujian Medical University Union Hospital Parkinson’s Disease, PD Parkinson disease, H&Y Hoehn–Yahr, MDS-UPDRS Movement Disorder Society Unified Parkinson’s Disease Rating Scale, RBDSQ REM sleep behavior disorder Screening Questionnaire, MoCA Montreal Cognitive Assessment.
  3. aNormally distributed continuous variables were compared using independent t-tests, and the results were reported as means along with standard deviations (means ±standard deviations).
  4. bCategorical variables were compared using Chi-square tests, and the results were reported as counts and percentages (n (%)).
  5. cNon-normally distributed continuous variables were assessed using the Mann–Whitney U test, and the results were reported as medians, along with interquartile ranges (medians [interquartile ranges]).
Back to article page