Fig. 2: Neuromelanin Levels Pre- and Post-Exercise.

A Average NM-MRI pre- and post-exercise. Axial image on the left shows the acquired NM image and the red box locates the cut-out sections shown. Top row shows the raw T1-weighted NM image (T1w NM), the bottom row shows the corresponding CR values. B CR in the SNc pre- and post-exercise by study participant. Individual lines are red if an increase was observed, blue if a decrease was observed. The solid black line represents the mean of our cohort, the dashed black line represents the baseline average multiplied by the expected decrease without intervention31.