Fig. 4: The frequencies and expressions of NKG2A in NK cell subsets are altered in association with disease duration.

Plots show A the frequency of NKG2A receptor expressing CD56bright NK subset, B the frequency of NKG2A receptor expressing CD56dim NK subset, and C the frequency of NKG2A receptor expressing CD56− NK subset, grouped by UPDRS score (<20, 20+). Plots show MFIs of NKG2A+ CD56bright NK subset (D), CD56dim NK subset (E), and CD56− NK subsets (F) grouped by UPDRS score (<20, 20+). Plots show G the frequency of NKG2A receptor expressing CD56bright NK subset, H the frequency of NKG2A receptor expressing CD56dim NK subset, and I the frequency of NKG2A receptor expressing CD56− NK subset, grouped by disease duration (<4 years, 4+ years). Plots show MFIs of NKG2A+ CD56bright NK subset (J), CD56dim NK subset (K), and CD56− NK subset (L) grouped by disease duration (<4 years, 4+ years). Data were analyzed one-way ANOVA or Kruskal-Willis test. Data represent mean ± SEM. *p < 0.05.