Fig. 6: Associations between composite ROI measures of tau-associated FA, MD and tNDI with the CDR-SOB in the DLBs group. Amyloid-β status is denoted by color-coded lines with 95% confidence bands (blue = amyloid-β negative, red = amyloid-β positive). | npj Parkinson's Disease

Fig. 6: Associations between composite ROI measures of tau-associated FA, MD and tNDI with the CDR-SOB in the DLBs group. Amyloid-β status is denoted by color-coded lines with 95% confidence bands (blue = amyloid-β negative, red = amyloid-β positive).

From: Influences of amyloid-β and tau on white matter neurite alterations in dementia with Lewy bodies

Fig. 6

Tau-associated white matter injury was statistically significant with CDR-SOB exclusively in the subgroup of DLBs who are amyloid-β positive. A + amyloid-β positive DLBs, A- amyloid-β negative DLBs, CDR-SOB Clinical Dementia Rating Sum of Boxes, DLBs dementia with Lewy bodies spectrum, FA Fractional anisotropy, MD Mean Diffusivity; tNDI tissue-weighted Neurite Density Index, ROI Regions of Interest.

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