Table 1 Population attributable fraction for excessive household pesticide exposure in different studies

From: Towards a methodological uniformization of environmental risk studies in Parkinson’s disease

Author, Year

Total

Multivariable analysis

Population attributable fraction

 

Group

PD

Controls

N with data

PD vs. Controls

Determinants of PAF

PAF (95% CI)

    

PD

Controls

Adj OR

95% CI

p-value

Adj OR

Prev. in PD

 

Payami et al. 1

Males

512

125

297

88

2.52

1.37-?

< 0.001

2.52

28%

17% (7-27%)

 

Females

296

290

193

206

2.85

1.87-?

< 0.001

2.85

35%

23% (12-34%)

Moura et al. 2

All participants

562

374

539

356

2.27

1.46-3.52

< 0.001

2.27

18%

10% (5-12%)

 

Males

293

165

282

156

2.19

1.18-4.04

0.012

2.19

20%

10% (3-15%)

 

Females

269

209

257

200

2.43

1.28-4.6

0.006

2.43

16%

9% (3-12%)

Narayan et al. 4

All participants

357

807

357

807

1.37

1.13-1.92

Not described

1.37

34%

9% (3-16%)

  1. Household pesticide exposure was tested for association with PD through a multivariate logistic regression analysis (described in the original studies), followed by PAF calculation for exposure. Adj OR adjusted odds ratio, CI confidence interval, PAF population attributable fraction, PD Parkinson’s disease, Prev. prevalence.
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