Table 1 Description of patient-derived and control iPSC lines

From: Upregulated ECM genes and increased synaptic activity in Parkinson’s human DA neurons with PINK1/ PRKN mutations

Line

Type

Sex

Age

Data used

Mutations

iPSCDAneurons4

Control

Male

43

RNA seq

NA

iPSCDAneurons30

Control

Male

71

RNA seq, Ephys

NA

JEA16

Control

Male

53

Ephys

NA

Red ion

PD patient

Male

75

RNA seq, Ephys

PARK2 R275W/WT + PINK1 p.Try90Leu fs*12/WT

PP1

PD patient

Female

48

RNA seq, Ephys

homozygous PINK1 p.Try90Leufsx12+ het PARK2 Arg275Trp in exon 7

  1. This table provides the details (age and sex) alongside the genetic characteristics of the patients and controls in the study. The mean age of control individuals was 56 ± 8 years (standard error). The mean age of PD patients was 61 ± 14 years (Standard error).