Fig. 4: A schematic of the riboflavin metabolism pathway.
From: Meta-analysis of shotgun sequencing of gut microbiota in Parkinson’s disease
Enzymes are indicated by EC numbers in squares. Metabolites are indicated in green letters and open circles. KEGG pathways are indicated by round squares. Arrows indicate decreased or increased in PD. Significant and non-significant changes are indicated by thick and thin arrows, respectively. Forest plots of six datasets are indicated for the five significantly changed enzymes. A right upper heatmap indicates the Spearman’s rank correlation coefficients between the five significantly changed enzymes and fecal SCFAs/polyamines. The square sizes represent the number of samples. Bars represent 95% confidence interval. Diamonds represent the mean and 95% confidence interval. The same EC numbers are labeled by a–e.
