Table 5 Cortical and subcortical abnormalities in PD participants with EDS and without EDS
From: Clinical symptoms and neuroanatomical substrates of daytime sleepiness in Parkinson’s disease
Cortical metric | Region | Hemisphere | Cluster size, mm2 | No. of vertices | Talairach coordinates | −log10 p value | ||
|---|---|---|---|---|---|---|---|---|
x | y | z | ||||||
A. Regression of ESS | ||||||||
Cortical surface area | Insula | R | 2058.91 | 4354 | 29.9 | 20.1 | 4.6 | 2.829 |
B. PD-EDS > PD-nEDS | ||||||||
Cortical surface area | Rostral middle frontal | R | 4069.27 | 5949 | 25.2 | 41.8 | 15.1 | −2.909 |
Supramarginal | L | 3525.14 | 8516 | −57 | −41.1 | 35.1 | −2.927 | |
Caudal middle frontal | L | 2076.84 | 3515 | −34.2 | 17.3 | 22.4 | −3.687 | |
C. PD-EDS < PD-nEDS | ||||||||
Cortical volume | Precuneus | L | 1523.91 | 2538 | −15.5 | −66.7 | 36 | 3.441 |
Subcortical metric | Region | Hemisphere | No. of vertices | MNI152 coordinates | ||
|---|---|---|---|---|---|---|
x | y | z | ||||
D. Regression of ESS | ||||||
Contraction | Putamen | R | 1239 | 19 | 11 | 0 |
Amygdala | R | 40 | 30 | −9 | −16 | |
Expansion | Amygdala | R | 44 | 28 | −7 | −23 |
E. PD-EDS < PDnEDS | ||||||
Putamen | R | 455 | 19 | 6 | −7 | |
F. PD-EDS > PD-nEDS | ||||||
Amygdala | R | 19 | 28 | −8 | −22 | |
