Fig. 5: Co-staining of striatal sections from rats injected with rAAV-human α-syn with the mAbs and an anti-aggregated α-syn commercial antibody. | npj Parkinson's Disease

Fig. 5: Co-staining of striatal sections from rats injected with rAAV-human α-syn with the mAbs and an anti-aggregated α-syn commercial antibody.

From: Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers

Fig. 5

Photos of representative immunofluorescence staining with the experimental mAbs (left) and the commercial anti-aggregated α-syn (MJF14, middle) and the merged image (right). Co-staining of MJF14 with mAbs (a) 10-9C8-C1, (b) 14-9E7-A1, (c) 17-9D12-A1, (d)18-3A5-H2, (e) 20-9E2-B8. Images represent areas with values close to the average obtained from triplicate staining that are shown in Table 4. Green: mAbs. Magenta: MJF14. White: Merged/overlap. Scalebar = 50 µm, applied to all photos. White arrows: examples of overlap.

Back to article page