Table 1 Cohort descriptives

From: MRI subtypes in Parkinson’s disease across diverse populations and clustering approaches

 

PPMI (N = 315)

EXPANd (N = 75)

KIMOVE (N = 136)

Barcelona UB-Clínic (N = 107)

PD combined (4 cohorts N = 633)

Control group (N = 233)

Age, years (median, IQR)

62.37 (14.16)

69 (8)

65.64 (13.56)

65 (16)

64.99 (13.79)

64.5 (13.3)

Sex (men/women)

199/116 (63% men)

44/31 (59% men)

91/45 (67% men)

67/40 (63% men)

401/232 (63% men)

148/85 (64% men)

Disease duration, years (median, IQR)

0.36 (0.53)

4 (6)

2 (5)

6 (9)

1 (3.66)

NA

Medicated (no/yes)

315/0

1/73

58/78

0/107

374/258

NA

Field Strength (1.5 T/3 T)

100/215

0/75

93/43

0/107

193/440

41/192

Education, years (median, IQR)

16 (4)

15 (4)

Missing data

10 (8)

15 (5)

16 (5)

Hoehn & Yahr scale (1/1.5/2/2.5/3/4)

135/0/178/0/2/0

0/0/58/0/17/0

33/0/56/0/19/10

22/5/57/12/10/0

190/5/349/12/48/10

NA

UPDRS part III (median, IQR)

20 (12)

31 (15)

Missing data

13.5 (11)

20 (13)

NA

MoCA (median, IQR)

28 (3)

26 (4)

Missing data

26 (2)

27 (2)

28 (2)

  1. Discrepancies in numerical values are attributed to missing data.
  2. Barcelona UB-Clínic Cohort from Hospital Clínic, Barcelona, EXPANd cohort from the Exercise in Parkinson’s disease and Neuroplasticity trial, IQR interquartile range, KIMOVE cohort from the Karolinska Imaging in Movement Disorders study, MoCA Montreal Cognitive Assessment, NA not applicable, PD Parkinson’s disease, PPMI cohort from the Parkinson’s Progression Markers Initiative, UPDRS Unified Parkinson’s Disease Rating Scale.