Table 2 Six months after surgery (V3), both conditions (OS and DS) showed significant therapeutic efficacy with regard to segmental (MDS-UPDRS III) and axial motor (FOG-AC) symptoms compared to Stim Off during the acute evaluation (i.e., 30 min stimulation periods); however, there were no significant differences between the omnidirectional (OS) and directional (DS) conditions
Omnidirectional | Directional | Stim Off | Stim Off vs. Omnidirectional | Stim Off vs. Directional | Omnidirectional vs. Directional | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | Mean ± SD | p value | z value | n | p value | z value | n | p value | z value | n | |
MDS-UPDRS III | 30.00 ± 13.55 | 30.72 ± 10.87 | 39.63 ± 12.92 | 0.001 | −3.298 | 15 | 0.003 | −2.985 | 15 | 0.521 | −0.641 | 17 |
VDR | ||||||||||||
Task accuracy | 0.71 ± 0.27 | 0.69 ± 0.27 | 0.65 ± 0.31 | 0.181 | −1.338 | 15 | 0.440 | −0.772 | 16 | 0.860 | −0.176 | 16 |
Task reaction time | 2.56 ± 0.63 | 2.51 ± 0.59 | 2.56 ± 0.38 | 0.379 | −0.879 | 14 | 0.532 | −0.625 | 15 | 0.925 | −0.094 | 15 |
Oddball accuracy | 0.94 ± 0.07 | 0.90 ± 0.21 | 0.89 ± 0.17 | 0.676 | −0.418 | 15 | 1.000 | 0.000 | 16 | 0.324 | −0.986 | 16 |
Oddball reaction time | 0.92 ± 0.23 | 0.90 ± 0.26 | 1.18 ± 0.51 | 0.061 | −1.875 | 15 | 0.002 | −3.131 | 16 | 0.227 | −1.087 | 16 |
SDR | ||||||||||||
Task accuracy | 0.27 ± 0.10 | 0.30 ± 0.07 | 0.29 ± 0.08 | 0.553 | −0.593 | 15 | 0.288 | −1.063 | 14 | 0.475 | −0.714 | 15 |
Task reaction time | 1.76 ± 0.78 | 1.73 ± 0.60 | 1.80 ± 0.68 | 1.000 | 0.000 | 15 | 0.925 | −0.094 | 14 | 0.532 | −0.625 | 15 |
Oddball accuracy | 0.64 ± 0.22 | 0.64 ± 0.21 | 0.65 ± 0.23 | 0.864 | −0.171 | 15 | 0.861 | −0.175 | 14 | 0.527 | −0.633 | 15 |
Oddball reaction time | 1.04 ± 0.41 | 1.04 ± 0.34 | 1.11 ± 0.42 | 0.826 | −0.220 | 14 | 0.363 | −0.910 | 14 | 0.875 | −0.157 | 14 |
FoG-AC | 14.83 ± 13.66 | 13.92 ± 13.32 | 17.83 ± 15.05 | 0.021 | −2.307 | 12 | 0.024 | −2.251 | 12 | 0.591 | −0538 | 12 |
CAPSIT | ||||||||||||
Steps | 38.36 ± 22.26 | 43.50 ± 33.56 | 38.75 ± 26.29 | 0.119 | −1.561 | 12 | 0.285 | −1.069 | 12 | 0.166 | −1.385 | 14 |
Time (s) | 33.07 ± 43.95 | 37.86 ± 58.97 | 37.58 ± 51.46 | 0.073 | −1.795 | 12 | 0.349 | −0.936 | 12 | 0.244 | −1.166 | 14 |
Freezing episodes | 0.93 ± 1.73 | 2.50 ± 5.97 | 1.67 ± 3.42 | 0.273 | −1.095 | 12 | 1.000 | 0.000 | 12 | 0.225 | −1.214 | 14 |