Fig. 2: SVHRSP treatment mitigates dysbiosis in the fecal microbiota in rotenone-induced PD mice. | npj Parkinson's Disease

Fig. 2: SVHRSP treatment mitigates dysbiosis in the fecal microbiota in rotenone-induced PD mice.

From: SVHRSP protects against rotenone-induced neurodegeneration in mice by inhibiting TLR4/NF-κB-mediated neuroinflammation via gut microbiota

Fig. 2

a Alpha-diversity result of gut microbiota using Shannon index. b Alpha-diversity result of gut microbiota using Simpson index. c PCoA plots showing beta diversity via weighted UniFrac analysis across various groups. d Relative prevalence of gut microbiota at the phylum level. e Relative abundances of Bifidobacterium and Allobaculum in the three groups. f Bar plot showing the overlap of amplicon sequence variants (ASVs) between Rot versus Con and Rot + SVHRSP versus Rot, presented as log2fold change. ASVs are listed with corresponding genus or phylum levels. g Overlap of KEGG pathways in fecal pellets between Rot versus Con and Rot + SVHRSP versus Rot, depicted as log2fold change.

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