Fig. 3: Fecal metabolism in rotenone PD mice and upon SVHRSP reversal. | npj Parkinson's Disease

Fig. 3: Fecal metabolism in rotenone PD mice and upon SVHRSP reversal.

From: SVHRSP protects against rotenone-induced neurodegeneration in mice by inhibiting TLR4/NF-κB-mediated neuroinflammation via gut microbiota

Fig. 3

a PLS-DA plots of metabolites among different groups. b Examination of the number of differentially altered metabolites from Rot versus Con and from Rot + SVHRSP versus Rot. c Boxplot showing the levels of different metabolites across various groups. d Pathway overrepresentation analysis of differential metabolites for Rot + SVHRSP versus Rot. e Heatmap of the Spearman’s correlation analysis between microbiota at the genus level and differentially altered metabolites among Con, Rot, and Rot + SVHRSP groups. *p < 0.05, **p < 0.01, ***p < 0.001.

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